Clonotril is clonazepam and Alpraquil is alprazolam. Both are benzodiazepines with similar side effect profiles, but different chemical structures. Potency is different, Clonotril 0.25mg is roughly Alpraquil 0.5mg. The half life of Clonotril is between 19-60 hours while Alpraquil is between 9-20 hours. Both are used for panic and anxiety disorders, but Clonotril is also used for seizures (U.S labeling)
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