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What is the difference between Cinvanti and Emend?

Answers (1)

Official Answer by Drugs.com 23 Jan 2018

There are several differences between Cinvanti and Emend. Cinvanti is FDA-approved for adults only for prevention of chemotherapy-induced nausea and vomiting (CINV), while Emend can also be used in children in certain circumstances. Emend is approved to prevent nausea and vomiting associated with both chemotherapy or surgery. Cinvanti is only currently available as an intravenous (IV) formulation given through a vein, while Emend is available as an oral capsule or an oral suspension taken by mouth, as well as an IV injection (as the prodrug fosaprepitant). When given IV, fosaprepitant is converted to aprepitant within 30 minutes.

  • Both the Cinvanti and Emend injection are approved in adults for the prevention of CINV in both the acute and delayed phase.
  • The Emend oral capsules can be used for prevention of CINV in both the acute and delayed phase in adults and children 12 years and older. The Emend capsules are also used in adults for the prevention of postoperative nausea and vomiting (PONV).
  • The Emend oral suspension can be used for prevention of CINV in adults and children 6 months and older.
  • Emend is available as a generic formulation for the capsule and injectable formulation, but no generic exists yet for the Emend oral suspension or for Cinvanti.

Review the product labeling for each medication to see other differences.

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