My doctor prescribed me a branded sertraline 50mg daily for two weeks for OCD (musical obsession). In the first two weeks, I felt great and the volume of music in my head has reduced significantly. I was able to think clearly and make clear decisions that were hard before taking the medicine.
Later doctor recommended the generic version of sertraline for another two weeks and increased dosage to 100mg. After taking it my symptoms came back and then he increased dosage to 175mg for another two weeks. So I'm on generic for a month now but I still do not feel good like when I was taking branded version? my symptoms are back too. Could it be a difference between these two versions that cause this?
Hi, emotional! The difference between the brand and generics is the inert ingredients that are used as binders, fillers, and coloring agents which may change from one manufacturer to another. Some people are very sensitive to these agents and report that the generics don't work for them. Your pharmacist should be able to check the formulations of the different generics and determine which is the same, or as close as possible, to the brand. If necessary, you can ask that the pharmacy special order that one for you. You might pay a few cents more for it but if it works it's worth it. Remember too that it usually takes 6-8 weeks for the medication to become fully effective. You may need to give it a bit more time. Best regards and I hope you're feeling better quickly. Wildcat
Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), Wolters Kluwer™ (updated 31 Aug 2020) and others.