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How much diazepam will get in a baby's system if the mother takes 5mg a day during pregnancy?

Responses (2)

DzooBaby 30 Aug 2013

Diazepam does cross the placenta so the baby gets the medication the same as the mother. Diazepam has been shown to cause problems in babies born to mothers taking the drug, especially early in pregnancy. Here is what the literature says:
Usage in Pregnancy:

An increased risk of congenital malformations associated with the use of minor tranquilizers (diazepam, meprobamate and chlordiazepoxide) during the first trimester of pregnancy has been suggested in several studies. Because use of these drugs is rarely a matter of urgency, their use during this period should almost always be avoided. The possibility that a woman of childbearing potential may be pregnant at the time of institution of therapy should be considered. Patients should be advised that if they become pregnant during therapy or intend to become pregnant they should communicate with their physicians about the desirability of discontinuing the drug.

In humans, measurable amounts of diazepam were found in maternal and cord blood, indicating placental transfer of the drug. Until additional information is available, Diazepam is not recommended for obstetrical use.

FDA pregnancy category D. If you take diazepam for anxiety, alcohol withdrawal, or muscle spasms, do not use this medicine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. Diazepam may cause low blood pressure, breathing problems, or addiction and withdrawal symptoms in a newborn if the mother takes the medication during pregnancy.

Factfinder411 30 Aug 2013

You have to talk to the neonatologist doc because not taking can put you into withdrawal and that's even worse for the baby. They will monitor you once to twice a week or they my wean you off.

It honestly up to you ob and neo doc whether the benefit out weighs the danger.

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