I got a cortizone shot today and my blood sugar has risen over 12 hours from 120 to 284. They told me it might raise glucose. I don't take insulin. I found that max dose of glipizide is 15 mg twice a day. I usually take 2.5mg once a day with Januvia 100mg once a day. I want to know if anyone out there takes a higher dose of glipizide with Januvia as I would like to take some more to lower my glucose. Please don't tell me to go to a doc. i will do that if I do not find someone who does this. thanks in advance, jan