I am in my late forties and have noticed that for the past year I have been more and more prone to reactions from things that never produced a reaction before. The main one I have noticed is when I have to take Ibuprofen or Naproxen for severe menstrual pain. I have started to have swellings around my mouth and on one occasion my eyelid swelled up. I have also started getting hives but this can happen at any time and I do not have to be on medication. The most common time I get this is about 6am in the morning and it wakes me up. But this could happen one day and not the next. I have also developed rosacea and some days I wake up with it all over my nose and tops of my cheeks, both pustules and papules. What is happening to me? I haven't yet seen a connection to anything I eat or drink (I have tried keeping a diary) but I feel like this is only a matter of time before it happens.