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What is the determining factor in prescribing Depakote DR vs. Depakote ER ?

Responses (1)

WildcatVet 11 Jul 2017

Hi, msrx! Since both medications are used to treat migraines/epilepsy/bipolar disorders one factor might be patient compliance and convenience since ER is once a day dosing and DR is twice a day.
Also, since DR is enteric coated it might cause less gastric irritation and better bio-availability in the intestine for sensitive or resilient individuals.
Regards, Wildcat

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