... problem. My mouth hurts and feels like it has small cuts. I saw that dry mouth is a side effect of Cymbalta so I requested a change and have been prescribed Pristiq. I have been researching and found that dry mouth may also be a side effect with Pristiq as well. Is it worthwhile to go through the transition? I have been instructed to try to ween off by opening the capsules and splitting it in half for 7 days, then down to 1/4 for 3 days. I also take cyclobenzaprine, and Zolpidem, which both also mention dry mouth as side effects. My mouth is so uncomfortable all the time. I am ready to try to stop taking both of these as well. I am scared of what side effects I may go through. Any suggestions? or past experience. I have been using Biotene toothpaste and mouth wash