I was on Depo on and off (but mostly on) for 18 yrs. I always found that the first 3 (ish) shots caused me to bleed erratically & sometimes constantly, & the 3rd or 4th shot stopped my periods all together.
If the bleeding is frequent and heavy, you will need to check with the Doctor that you do not become anaemic, until things settle down on the Depo.
Everyone is different, but that has always been my finding with this drug.
Hope that helps
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