I am on depo lupron 11.25 shot n i have a question in regards to blood pregnancy test. Now when my doctor put me on this, i asked if i need to be on a non hormonal birth control n he told me that i didn t need to. Which i have read is not true. I have had 2 negative blood pregnancy test n 1 negative urine test aswell. Now my question is can i trust i m not pregnant? Does depo lupron affect resilts of pregnancy blood test result? I know may sound silly, n maybe i m being overly paranoid! I have search for answers online n couldn t find answer. Thanks for taking time to read my question n if anyone has an answer, i would love to hear. Thank again.