I've currently been on depo for about a year and a half. Recently I've ran into a very large handful of women who have said that being on depo has caused them much stress in conception, it has caused cysts, thickened endometrial lining, complete loss of ovulation, you name it. I'm only 18 so kids will not be in the picture for quite some time but if depo is as bad as these people have claimed I want off now!!! Has anyone else experienced the likes of this, does anyone know if these are likely depo related? And last but not least is there a birth control that is just as effective but better for my body that I can replace it with?