I take 400 mg of Kadian,2 times a day an up to 4-30 mg of instant release Morphine for break through. I can go up to 1600 mg a day, but I also have Hep C which means I should not be taking but the vary least amount of meds. So it won't hurt the Liver. Is there any thing I can have done or take but no surgery or operations. A small amount medicine with large results.