I have sever panic attacks and aniexty After trying other drugs (bus par,effexor, and many others ) they never got to the core of the issue always felt a little better but still had a hard time being alone and driving. My dr prescribed me 50mg of zoloft for 7 days and 100mg thereafter. Let me say the first 7 days were hard. I fell a little better but my aniexty has not subsided. I read that it takes a while to get in your system but feel as if I am getting worst not better. Any advise ???