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I’ve been on Cymbalta ever since it came out. Suddenly my depression is back. Not working?

Responses (2)

mundling 7 days ago

Hey Susan!

I haven't heard of Cymbalta suddenly not working, it may be or it could be that your spirit is sinking deeper into depression and you need an additional medication such as abilify. That's what happened to me. It has made a profound difference in my mood.

Best wishes!

Hugzzz
pamela

Votes: +1
WildcatVet 7 days ago

Hi, Susan! Any antidepressant used long term can stop working eventually; the unscientific term for it is "poop out".
Discuss this with your doctor because some options are a dosage change, the addition of an add-on medication such as Abilify or Rexulti, and sometimes switching to a different medication.
Your not alone! This is a common occurrence.
Best regards, WildCat

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