I use to have the mirena iud but then I had complications with it so I tried Depo in Sept 2014. I was nauseous all the time, I couldnt eat, I was losing weight. I had constant migraines and I only came on my period once a couple weeks after getting the first shot. I was due to get my next shot in Dec 2014 but due to the side effects I encountered I never went back for my second shot. Now it is nearly May 2015 and still no cycle however I have sore and tender breast symptoms. Still nauseous and occasional headaches. Any answers???