My son (age 15) was diagnosed with crypto Aug 7th and it is now Sept2nd and he still have terrible bouts of stomache pain that buckle him over and he breaks out in a sweat. He is sick again today after being ok for 3 days. Any ideas on how long this is going to last?
First of all I am truly sorry for your son.-
Cryptosporidiosis is typically an acute short-term infection but can become severe and non-resolving in children and immunocompromised individuals. In humans, it remains in the lower intestine and may remain for up to five weeks.The parasite is transmitted by environmentally hardy microbial cysts (oocysts) that, once ingested, excyst in the small intestine and result in an infection of intestinal epithelial tissue.
The life cycle of cryptosporidium parvum consists of an asexual stage and a sexual stage. After being ingested, the oocysts excyst in the small intestine. They release sporozoites that attach to the microvilli of the epithelial cells of the small intestine. From there they become trophozoites that reproduce asexually by multiple fission, a process known as schizogony. The trophozoites develop into Type 1 meronts(unusual for a major group of organisms, the apicomplexans are as yet identified as exclusively parasitic. ) that contain 8 daughter cells. These daughter cells are Type 1 merozoites, which get released by the meronts. Some of these merozoites can cause autoinfection by attaching to epithelial cells. Others of these merozoitesbecome Type II meronts , which contain 4 Type II merozoites. These merozoites get released and they attach to the epithelial cells. From there they become either macrogamonts or microgamonts. These are the female and male sexual forms, respectively. This stage, when sexual forms arise, is called gametogony. Zygotes are formed by microgametes from the microgamont penetrating the macrogamonts. The zygotes develop into oocysts of two types. 20% of oocysts have thin walls and so can reinfect the host by rupturing and releasing sporozoites that start the process over again.The thick-walled oocysts are excreted into the environment. The oocysts are mature and infective upon being excreted. They can survive in the environment for months.-
Take care and I hope your son gets well soon, it should not be long
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