300mg of Venlafaxine is a high dose. You shouldn't take St. John's Wort without discussing it with your doctor.
If you feel that your depression isn't controlled with that dose of venlafaxine please let your doctor know and he/she may be able to help by either adjusting the dose of venlafaxine or adding another medication to it.
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St. John's Wort - I started taking St Johns Wort 3 days ago its 450mg per tablet but it says on the?
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