After reading your comments all night I have come to some conclusions.i will try contrave titrating the dosage,after food ,drinking a lot of water.i was always a slim person even after my second child (140 pounds). Since then i straggle with hormonal therapies,hysterectomy,migraines, menopause, 220 p at the moment,exercising twice a week and desperate for loosing weight as i cannot see myself in the mirror.Nothing else works,i do not eat a lot,not having sodas,looking forward to try it.Any other recommendations?any suggestions??thank you in advance. 45y.o. female