I have been on duloxetine, venlafaxine for over 20years. Recently tried sertraline, escitilipram, pregabalin. These have helped my OCD 70% but none have ever help d my severe anxiety and low mood. I am so desperate to get better, I read all the books try cat etc etc but I am so nervous I find everything overwhelming, lost a good job, marriage and feel hopeless. I am now 47 and my psychiatrist wasn’t keen to change but clearly SSRI/SRNI aren’t helping enough. I am hopeful but so scared when changing if they just don’t work. Thank you.
Clomipramine apparently has above average response rates for OCD. (not a wonder drug so It may or may not work).
It is a TCA and slightly older medication. It may have some side effects.
Most common side effects are: sexual related, dry mouth, sleeping changes, weight gain.
When you go to 200 or 250 mg be careful and check with doctor.
Its worth a shot if you have moderate or severe OCD. Just follow instructions.
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