My 28 yr old son has chronic pain from osteoarthritis due to foot surgery as a baby. The only med he could tolerate was Darvocet due to allergic reaction to opioids with severe itching. When Darvon/Darvocet was discontinued he started Tramadol but pain relief only brought him down to a 5-6 on the 0-10 pain scale. He also takes a daily NSAID but without the Darvocet daily pain is leaving him with a grim future. He does most all other modalities for joint and bone pain.