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Chemical structure of avastin?

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Rajive Goel 25 Sep 2010

The chemical structure seems not to be available, however Avastin Bevacizumab is a recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF) in in vitro and in vivo assay systems. Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF.

It is an anticancer product, hope the info is useful?

scientistsahai 14 Dec 2010

Avastin is a humanized mAB for the treatment of metastatic cancers. It works by blocking the VEGF-A which stimulates the growth of new blood vessels.

Bevacizumab is produced in a Chinese Hamster Ovary expression system and weighs approx 149kDa.I

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