Hello Rescue Folks,
As I understand it, the active ingredient in Certifect IS effective on mange, but it must be repeated every month. If not repeated monthly FOR LIFE, it is likely the mange will reoccur. Certainly there is a web site more suitable than this one for help with veterinary related questions. I'm just giving you my best guess based on likewise being an animal lover/rescue organization.
God Bless you for all that you do for animals.
4N Substances aka Frenchie
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