I have read all the reviews and seems like a miracle drug, I have not tried it yet,but at 52 years old I have already had a spinal fusion and knee replacement, constant pain, pinched nerves, pain radiating down both legs and radiating from the pinched nerve in my back as well, shoulder bursitis in both shoulders,osteoarthritis, even with percocet 10s. I am going to ask my Doctor to try me on Celebrex instead. But nobody mentioned anything about side effects, has anyone had weight gain/ loss?