My doctor prescribed me carvedilol 3.125mg but told me to take it once daily rather than twice a day. The rationale was I was on a low dose of a 1x a day drug (Bystolic) and he was trying to keep my dosage low. My concern is - if this is supposed to be taken 2x a day am I putting myself at risk for 12 hours or is merely lowering the dosage, I am unable to find anything on the internet about a 1x a day recommendations.