This is not recommended do to the fact that Suboxone (Buprenorphine) Is an antagonist to other Opiate/Opioids. If you take Methadone while the suboxone is in your system you most likely experience withdrawal symptoms. The manufacture stated that the Buprenorphine was in some patients system for up to 11 days. I would recommend waiting at least the approximate amount of time that Buprenorphine is in you system which is approximately 40 to 88 hours. Remember this differs from person to person. You won't feel the effects of Methadone if you take it while Suboxone is in your system. If you take it the same day it probably won't do anything or may cause withdrawals. Hope this helps! Good luck to you!
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