and take oxycodone 410mg 4 times in severe pain the oxy tens are not working,but fentanyl helps,but not for breakthrough.i suffer from several herniated disca,arthritis in faucet joints,fibromyalga,type one dtabetes with severe neuropathy from my knees down.all i do is cry,any advice would be greatly dr. mentioned opana to me ,but i wanted to do more research first.if anyone knows what dosage i should take to improve my quality of life that woulld be great.