The "official" answer is indeed "No, do not split or crush." But please double-check with your doctor (pharmacists are not very familiar with this med). While the controlled-release mechanism of many medications is defeated by crushing or splitting, with some it's OK -- it all depends on the method the pill uses for controlling release. Also, note that there are some generic versions of Trental that are smaller than others. I use Mylan, which is very large. I once used Apotex which was quite a bit smaller, but as of Oct 2010 the FDA is still enforcing a year-long ban on sale of all Apotex generics in the US. I don't know the size of the Teva version, which I believe Walgreens and some others use, based on calling and surfing. But FWIW, I read that Teva is still having intermittent Trental shortages.
- Trental Information for Consumers
- Trental Information for Healthcare Professionals (includes dosage details)
- Side Effects of Trental (detailed)
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