I have been taking 150 twice a day, and it has not helped fib and blood pressure,, up it to 225 twice a day, plus 5 mg of bystoic and I have higher pressure now then before and it has not stopped the a-Fib and I don't like taking it as mouth taste awful and frankly I do not like side effect, but doctor doesn't seem concerned... they say go to drug store for blood pressure check and it was so much higher there and I don't trust those machines at all