After taking the drug daily (prescribed for occasional episodes of gout) for about two months, my husband started developing this problem. At first it was only on exertion; now it occurs even during rest periods. Additionally, at night when he lies down, he frequently experiences wheezing. Coughing to move what he perceives to be fluid in the bronchi results in a dry, non-productive cough. I read on your site that less than 1% of those taking Alllopurinol have experienced bronchospasm and/or asthma. Is there any evidence to support this additional complication? On the off chance that it could be the drug causing this problem, he stopped taking it day before yesterday. While there is no notable improvement yet, I have hope.