I have been on Kadian for the past two years for a fusion at L-5/S-1. I have a plate and four screws that were broken in half in a car accident. I was taking 300mg of kadian every 12 hours. I did fine no side effects. My insurance did not approve the kadian any longer and made me move to ms contin 100mg 3pills every 8hours. I HATE it. I have an anxiety disorder treated with xanax, but since starting the ms contin I have experienced swelling of the hands, feet, neck, face, throat, vein issues, brusing under viens, hot red skin, high blood pressure and blurred vision. I feel like im going to die. i have been to the er and the have done the blood work up and scaned me for a blood clot and pe and everything was great no problems but my symptoms are getting worse. I am living in fear of dying every second. I have 3 kids and need to figure this out. i have to be there for them. I know both drugs are morphine... could the ms contin be doing this to me? side note ... I take dilaudid for break through for years no problem... pleas help
The active ingredient in the Kadian and the MS Contin is the same, morphine sulfate. The only thing I can think of is you are having a reaction to something in the inactive ingredients of the MS Contin. The inactive ingredients in MS Contin include: cetostearyl alcohol, hydroxyethyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, talc and titanium dioxide. The Kadian contains the following inactive ingredients: hypromellose, ethylcellulose, methacrylic acid copolymer, polyethylene glycol, diethyl phthalate, talc, corn starch, and sucrose. Upon comparing the two, the only major difference with the MS contin is the magnesium stearate. You may have an allergy to this substance.
I would definitely discuss these symptoms with the prescribing doctor. I don't think you are going to die, but your symptoms are not to be ignored. Please consult the prescibing doctor and have him contact the insurance company so you can get back on the Kadian. All the doc has to do is let the insurance company know of your adverse reaction.
This is a true story. I was once a a medication and they switched it to a generic. The Pill was originally white and the generic was purple. I had some very similar symptoms, I mean just like you. I did a test in a lab, yes I have access to a lab, and found that I was allergic to the FD&C blue dye in this pill. Or more precise a particular coloring in the pill. Later on I found this same coloring in IVP dye for kidney stone detection( they inject then x-ray) and prylosec ( the purple pill). I am not saying this is at all your problem but... it is worth looking into. Many people I know have had adverse reactions to generic pills and it is because of the physical and chemical make up. It is an allergic reaction. When they take what they took before or a pill that does not contain that dye, the syptoms go away. Please this may be way off from what is happening to you, but it is something you might want to ask when you speak to DR. Most Dr. do not know this.
Is the pill a different color then pills you have taken in the past? Or it can be another property of the pill that you might be allergic to. Sounds far fetched but worth asking.
I wish you my very best.
I completely understand I heard the same words except from the pain specialist who made it clear that some of these drugs it's the inert things in them or the fillers, I had problems with MS Contin like you before my fall last winter I was on Dilaudid and was able to tolerate but it took going through two manufactures, Now I presently take Opana ER and I don't have any problems taking it. I noted the extreme redness and could even feel a warm effect to my body, I don't think dying will be the issue it made me feel so medicated (that was with 100mg every 8 hours, it may be either the dose or it may be that the doctor needs to work with you in order to find a medication that does not cause these types of problems, maybe talking with him/her and explaining just how you feel will cause the doctor to try and help you find a different regimen, I encourage you to pursue this with him/her. and I wish you only the very best
I agree that you are having an allergic reaction to something in the new med. I have an allergy to glycols, which are found in the inactive ingredients of some meds, and I can die from taking it. Some pills are even sprayed with Opadry clear - and that has glycols in it. So it is very possible for you to be allergic to one of many variables. All my dr has to do is have his office staff call my prescription company and tell them I have an allergic reaction and I get the brand name, etc, whatever is needed. So tomorrow you could have your old medicine back. And you need to do it tomorrow!! Allergic reactions can increase the more you are exposed to the allergen. Which means first thing tomorrow morning, or sooner if your symptoms get worse, you need to contact or go to your doctor, tell him your symptoms and have his staff get to work getting you the Kadian. You may not
make it until Monday - I am serious. If you start to have any wheezing or coughing or break out in hives call 911 and get to the ER. Make sure someone who is with you knows what is going on, or write a note explaining this new medicine and what your reactions are and pin it to your body if you have to be alone while still on the MS contin. You can't stop taking it - you'll go through withdrawal after ?12 hours or so. I know about these reactions all too well from stopping breathing myself. I was on a medication with glycols in it and i had a rash all over my face and was having horrendous migraines all the time. The ER staff, my primary care Dr and my dermatogist never connected it to an allergy. Allergies can and do kill - your body is telling you big time that this medication is dangerous for you - listen to it. It's toxic to your body. Drinks lots of water, take Vit C, a good multivitamin - flush your body out and you should be feeling better soon. Take care -
As the others have said, it is likely an inert ingredient causing the problem. Your Dr might be able to appeal to your insurance company that you cannot take the MSContin and maybe they will allow and pay for the Kadian. Have you tried several manufacturers of morphine sulfate ER? It might also help to try a drug from a diffeent manufacturer. As Laurie said, if the magnesium is the culprit, ask the pharmacist which manufacturer makes one without this ingredient. You could try this while your Dr is appealing to the insurance company. There is also the option of paying out of pocket, but I know that Kadian is very, very expensive.
its not the ms contin i take that and i have nothing like that although it is diff for everybody so ... my guess is the mix of both thath and the dilauded that stuff is no joke im on 30 mg of ms contin 2 a day and 3 ten norcos a day then .25 xannies 3 a day which does nothing for me i need atleast 2mg 2 to 3 a day. but my guess is the dilauded dude
I agree with everyone's responses on here and I do strongly advise that you speak with your doctor, and if he can't see you then go to his office and just sit there and wait until you annoy them enough that they see you! Insurance companies will pay for the brand name medications if your doctor writes for Kadian and marks the box on the script that "Brand Name Medically Necessary". It will take a lot of work and paperwork to get the brand name of Kadian but it will be worth it in the long run. There are other medications that can help your pain, and until you know what it is that you are reacting to it will be hard to make a good sound judgement on what it is that you can take. You can develop an allergy to a medication after taking it for a long time. I know this because I did... and it almost killed me. You have to be aggressive with this doctor and show him the physical reactions that you are having.
Unforturnately, sometimes you have to get angry and respectfully tell them that you know your body and you know that something doesn't feel right!!! I will keep you in my thoughts and prayers and I wish you the best of luck and as many pain-less/free days as possible.
I realize this is from 2 yrs ago but I thought I must answer in case anyone else is now having that same problem. My insurance cut me off Kadian and wanted me to take the mscontin. Same med: morphine, with the same 'dosage' of 200 every 12 hrs. The symptoms you had when you switched were withdrawl symptoms (just like mine). Miserable and you feel like you are dying. I am surprised the ER dr. didn't pick up on it but very few dr's even know what 'Kadian' is unfortunatly - it's just morphine.
I found out Kadian is 24hr released, mscontin is 12hr. But my Dr. said it's more like Kadian 12hr and mscontin is 6-8 hrs. So you are going through withdrawl twice a day. I have been SO sick with this mscontin. For a lot of people spacing the dosage of the mscontin to 3 or 4 helps maintain that level in your system. I was 200 Kadian 2x daily. Mscontin 150 2x (broke 1 in half) and took the a 50 halfway between each 150 dose. If that makes sense. After a while you can get used to it but it is NOT EASY. If your dr. can provide you with MSIR Mscontin 30mg short acting tabs for breakthru pain can help the withdrawl symptoms, which are miserable - i couldn't function. It's criminal for insurance companies to deny generic Kadian when it's only $300 more a month than mscontin ($1200). But get used to getting meds cut with obama care. It's starting and everything else I take has been denied. They want you to try 'other options' which do not work as well. Bare bones. Pretty soon nothing will be covered - I've had generics denied as well. If anyone has any solutions perhaps I would be very interested to hear if we can do anyting.
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