I have been on niaspan for 9 months and was on simivistaton for about a month of that. I was on 80mg of simivistaton and 2000mg of niaspan, now just 1000mg of niaspan, i have been complaining of pain in chest tightness and tender to the touch all right in the sternium area. I have had 2 angeograms since the heart attack 9months ago and everything looks good. I also had palpations every since going on these meds, plus my C K blood tests were in the 400 range. Thanks for any advice you can give me , anthony 42