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Can Niaspan cause eye puffiness? After only 1 week of 500 mg my eyes were much worse?

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Marvell 16 Mar 2011

The known side effects of Niaspan does not state anything about puffy eyes as such, but I guess it is possible. The known ocular side effects are:

Niacin appears to cause a reversible toxic cystoid maculopathy in approximately 0.7% of patients taking at least 1.5 grams daily. The maculopathy typically has been reversible upon discontinuation of therapy.

Ocular side effects have included amblyopia, sicca syndromes, blurred vision, eyelid edema, and macular edema.

https://www.drugs.com/sfx/niaspan-side-effects.html

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