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Can I use the Metronidazole together with the Clindamycin for Gardenella?

Responses (1)

suzanne66 22 Jan 2010

You will need to ask your doctor.
Are you pregnant? Are you referring to the tablets or cream ?
It would seem that treatment is usually metronidazole or clindamycin, not both together.
This is from http://www.fpnotebook.com/Gyn/ID/BctrlVgns.htm
Management
Non-Pregnant
First-Line: Oral Metronidazole (Flagyl)
Flagyl 500 mg PO bid for 7 days
Clindamycin Cream (2%) 5g PV qhs for 7 days
Pregnancy:
First Trimester
Avoid treatment if possible in first trimester
Clindamycin (Cleocin) 300 mg PO bid for 7 days
Clindamycin Cream 5 grams PV qhs for 7 days
Metronidazole Gel PV bid for 5 days
After First Trimester
Metronidazole (Flagyl) 250 mg tid for 7 days
Consider with Erythromycin 333 mg tid x14 days
Clindamycin 300 mg PO bid for 7 days
Resistant or Refractory Cases
Metronidazole 500 mg PO bid for 14 days (preferred)
Consider treating sexual partner and patient
Male urethra may be co-infected
Based on anecdotal reports (evidence lacking)
Other options
Clindamycin at above dose
Povidone-iodine gel OR suppository (Betadine)
Apply vaginally bid for 14 to 28 days ($59)
Recurrent Bacterial Vaginosis
Treat as refractory cases above
Consider maintenance therapy
Induction: Metronidazole gel (0.75%) qhs x10 days
Maintenance: When wet prep with no clues, pH lower
Metronidazole gel twice weekly for 3 months
Treat concurrent Candida if present
Fluconazole 150 mg qWeek

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