I am assuming you mean, can you just take an antihistamine just before you go somewhere, where your allergies might be activated.
Yes, you can. It might be better to take it at least an hour or so before so that the antihistamine can be absorbed and it starts working. If you don't have the allergen in your surroundings daily (and you don't suffer from allergy symptoms) then you don't need to take your antihistamines daily.
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