am taking exemestane since dx with breast cancer a year ago and now have UTI so was prescribed Cipro. Safe to take both at same time?
Interactions between your selected drugs
No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.
Other drugs that your selected drugs interact with
exemestane interacts with more than 50 other drugs.
Cipro (ciprofloxacin) interacts with more than 300 other drugs.
Interactions between your selected drugs and food
ciprofloxacin ↔ food
Applies to: Cipro (ciprofloxacin)
ADJUST DOSING INTERVAL: Concurrent ingestion of dairy products (milk, yogurt) or calcium-fortified foods (i.e., cereal, orange juice) may decrease the activity of certain oral fluoroquinolone antibiotics. The mechanism is chelation of calcium and the quinolone, resulting in decreased bioavailability. In the case of orange juice, inhibition of intestinal transport mechanisms (P-glycoprotein or organic anion-transporting polypeptides) by flavones may also be involved. One study reported an average 41% decrease in maximum plasma concentrations and a 38% decrease in AUC when ciprofloxacin was given with calcium-fortified orange juice instead of water.
MANAGEMENT: Dairy products or calcium-fortified foods should be ingested at least 2 hours after or 6 hours before fluoroquinolone administration.
All the best and take care.-
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