I started butrans 10mg patch on Monday at 3pm felt relief by Tuesday morning! No pain at all! Was able to live again do things I hadn't done in years! Felt great! Tuesday night still no pain but i didn't sleep at all all night finally took a muscle relaxer and got a few hours of sleep Wednesday morning and I have been so sleepy and can feel the full effects of the medicene today drowsy and nauseous little dizzy. So today was the full third day of the patch. My question is my patch has started bubbling up and itching like crazy and i would really like to replace it with a new patch even tho it's 4 days early, so question is will I still have pain relief if I replace it now or will my pain come back before the new patch starts working? Can anyone help with this!!!