Wondering if anyone takes Buspar along with Cymbalta? I just check the the drug interaction and it says there a major interaction with the two and can result in serotonin syndrome. And now I'm freaking out! I also take Xanax three times a day a low dose. Just until the Cymbalta/Buspar kick in. Is this too much at one time. For example I took 0.5 Xanax at 12 today because I needed it then I took 10mg of Buspar at 2pm because that's the normal time I take it. Now I feel really tired. I also take the Cymbalta in the morning with Cuspar at the same time. I wonder if I should take them at different times? Thanks for your help! I'm just following doctors orders.