I've been taking generic Bupropion XL 300mg once a day for about 2 years. I got a new refill last Sunday and started experiencing a rapid heart rate within a couple hours of taking it.
I didn't immediately associate it with Bupropion but I've since eliminated any other drug/lifestyle changes and this is still happening, always within a couple hours of my dose. According to the bottle label, it's the same manufacturer as my previous supply (mfg code is "PAR" and pills are stamped "A 102" -- internet tells me Anchen Pharmaceuticals, a subsidiary or Par Pharmaceutical).
I would always choose brand name Wellbutrin or zyban not generic. I have read many reviews that say generic Wellbutrin is inferior with strange side effects. I get that it’s the same as you’ve been on but why not try brand and see the difference.
30 Jul 2018
The same thing is happening to me right now. Ever since I got my refill on July 13th, 2018, I have been anxious, depressed, tired, crying, and just feeling terrible. I have a rapid heart beat also. My bottle says PAR A102 also, but I swear it is not the same. I emailed someone at PAR to ask if they changed labs. Hopefully, he will tell me the truth.
20 Jan 2019
I’ve been on Bupropion 300xl for 15 years. I could only take Par mfg. but since I started taking the last month or a bit more I have gotten so depressed and tired and anxious. There is something not right about this. I had this happen once before but that was when I switched to a different manufacturer and quickly went back to Par paying out of pocket. Now the Par is doing it. They must have changed something in their formula. I’m at a loss as to what to do. Anyone get any answers yet as to if they changed??
20 Jan 2019
If your budget or insurance allows, you might want to look into getting branded. I get mine from Costco up here in Canada, but I hear there might be issues getting branded in both the US and UK. Learned my lesson about generic brands vs branded before.
Was switched to generic without asking me (was informed of the change), and after 2 months I had to get them to order branded again. 2 weeks later things evened back out again.
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