... Zoloft and it was awful. Then to Prozac and that was hell. 3-4 hours of sleep a night for eight weeks. This was all thrugh my nurse practitioner. Said she couldn't help me anymore. I tried to find a psychiatrist and to no avail. I called 20 and either they did not take new patients, my insurance or mostly never called me back. So I went on doctor on demand and met a wonderful psychiatrist Nikole. Anyways startd me on 100 mg per day. After a month I felt better, but after that I felt worse. Now she put me on 100 mg in the am and 100 mg in the afternoon. So this new up has only been a week. Please tell me how long I have to wait for it to kick in. I am at my wits end with this stuff. The Prozac made me lose 10 pounds and am a tiny person. I sleep ok. I force myself to eat. but I feel like a shell of a person. Please help. Any info is appreciated!!