I've been taking Loestrin Fe 1.5/30 for about 10 months. I missed one day and took two the following day. It's been about 4 days since I took two pills on one day and I'm having pretty heavy break-through bleeding. I also cycle my packs together so I haven't actually had a period in about 9 months. I don't know if it's relevant or not but this bleeding is super annoying.