I am 46 and had a p.e. last Nov. I am taking warfarin. I am also diabetic type 2. I haven't seen a hemotologist yet but my primary doctor seems to think I would be taking it the rest of my life. I don't have a personal history of clots; however, my sister had the same thing one month before I did and my mom had p.e. about 3 years ago. My mom was able to get off of warfarin after about a year.