I recently found out I had a pretty bad yeast infection, with two remarkably big fissures on the top and bottom of my vagina. I went in to see a nurse practitioner with prescribed me metrogel-vaginal and gave me one pill of Diflucan at the office and one two days later. I tried apply polysporin to the fissures to help them heal, but it only got worse. Two days later I noticed it started to get a few blisters and another fissure on my labia.