Many prescribers are comfortable choosing one of the selective serotonin-reuptake inhibitors (SSRIs), such as Celexa, Zoloft, and Lexapro. They are primarily indicated to treat depression, but their use in treating OCD is now pretty common. Side-effects include drowsiness, impotence, and dry mouth. They usually take several weeks before any noticeable therapeutic effect occurs, and there is no evidence to recommend their long-term use for OCD.
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