Hi, I am allergic to Bactrim (sulfa drugs) and all i get is hives (all over). I was prescribed the drug once and all I took was one pill and broke out into hives. My husband has been using Bactrim DS and that seems to be all the doctors want to put him on for his sinuses. One time he kissed me on the cheek and later that morning I had a small batch of hives on my legs. So my question is, if I take benadryl while my husband is on Bactrim DS, do you think I will still get hives if my husband kisses me or what not?