I have been on 40mg three times a day of oxycontin for the last five years due to a liver in poor state.i have severe muscle cramping and pain 24/7.i am given 180 tabs per month,and this last batch does not work at all.this is the second time in five years i have encountered this problem.got last refill 4 days ago,took usual 40mg dose in morning and no effect.yesterday took total of 300mg throughout the day and no relief what so ever.i now have to go see my doctor once again over this issue.is it possible to get a bad lot.i do realize it is strictly monitored,but something is going on.i also notice such as the first time this happened that there is next to no smell to the pills,usually there is.this medication has worked wonders for me,and without it i would be in bed all the time.