I have been on copaxone for 2 years. In the last year I have had more and more reactions. They are increasing and are closer together. I have always had site reactions but this is the diff breathing chest tightness massive headaches. It is hard to believe that these can't cause any long term damage. They did not bother me at first because I knew the reactions only lasted 20 min. It makes me nervous that my reactions started after a year of use, increase the amount of them and the pain is more intense. Recently My head has felt like an I have been hit over the head with an axe. I stop the med 4 days now. I really have not felt well since. Decreased energy, decreased appetite, nausea and dizziness and increased belly aches.