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Are there 3ed gen antihistamine?

Responses (1)

Anonymous 5 Sep 2010

Yes there are.-

Third-generation H1-antihistamines are the active enantiomer (levocetirizine) or metabolite (desloratadine & fexofenadine) derivatives of second-generation drugs intended to have increased efficacy with fewer adverse drug reactions. Indeed, fexofenadine is associated with a decreased risk of cardiac arrhythmia compared to terfenadine. However, there is little evidence for any advantage of levocetirizine or desloratadine, compared to cetirizine or loratadine, respectively
There is some controversy associated with the use of this term.

Systemic:
Levocetirizine
Desloratadine
Fexofenadine

Take care.-

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