Last month I had a severe urinary tract Infection (bladder, kidney). My Doctor at VA medical center prescribed 2 antibiotics. I told also told them I am allergic to Bactrim. Within a week I developed a very painful yeast infection. Then I was treated with Flucosinol (antifugal) which cleared it up. However, one of the antibiotics given to me was called Dapsone. I was prescribed that because I am HIV & my Dr. said it would prevent PCP. Although, I have never been sick, the Dapsone nearly killed me. My whole body brokeout in a rash and hives, my throat hurt with difficulty swallowing, my lips were swollen, I developed blisters in my mouth, some of which were blood blisters and my nose started bleeding. I went to the ER & was prescribed antihistamines & taken off the Dapsone. The next morning my face, eyes were blood red & burned. My skin had heat to touch. The next day the redness finally went away & during the day I had a headache radiating to my left eye. I then took a nap & woke up 2 hours later. When I looked into the mirror I noticed my vision in the left eye was blurred with black peppered dots, lines, circles. I have never had problems with my eyes in my life. Back to the ER, check for retinal tear, etc. (had to wait 4 hours - ridiculous)! I was told I had what is called floaters & dry eyes. All in all, I firmly believe based on my story here, my eye problem was caused by Dapsone. I also noticed that I have tremmors now in my hands & a ringing in my ears that has not gone away. I still have a mild rash (looks like measles on my upper torso & arms) I did not experience itching - just burning. The VA acts like it is no big deal & denies the medicine caused the eye problem. I firmly believe that it did! This is too coincidental. Before I went to VA I was never sick, not I have been terribly ill for over 2 months. It has been deeply debilitating. I am an artist & I have difficulty even writing my name because of the hand tremors. I feel my life is ruined.
Are my side effects caused by Dapsone & Bactrim?
Added 30 Apr 2010:
Forgot to mention that I am on a coctail of HIV meds (horrible), but have so far had good results. The first 2 weeks made me sick (headache, dizzy, complete exhaustion . . . over all yucky feeling - 11 pills a day. So far I feel like my old self again, except for my eye & the hand tremors. I am sorry to say my previous husband died 8 years ago & left me with a lifetime present. I had no idea he was doing drugs (God knows what else), but all I can do is focus on staying well. I don't think this disease will ever be cured. I am sick of taking so many pills. I have to if I want to live.
You can view a list of Dapsone side-effects here:
Blurred vision and ringing in the ears are both common side-effects of Dapsone. It also can cause temporary peripheral neuropathy (nerve damage) which could account for the burning sensation and tremors.
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