I was on 25 mg of amoxapine for 6 weeks when it just turned on me and stopped working. It was causing increased anxiety, increased depression insomnia,confusion and a general feeling of being disconnected. My Doc told me to wean off by taking 1/2 the dose for three days This is day two. He put me on 10 mg of noratriptylne. The problem is I feel terrible today really disconnedted unable to function very depressed and anxious and having trouble talking and doing the simplest of tasks. As the day progresses I am feeling a little btter but really don't want to take the last dose tomorrow am. I have called my Doc but no response yet Any ideas? I always get good feed back from this forum