I've been prescribed these patches for several years & they've worked as well as possible. However I recently went into severe withdrawal symptoms- tremors, racing heart, nausea, & severe breakthrough pain when I put on new patch. Yet when I changed to another separate, new box of patches with different Lot # on it, I was okay again. I just got new prescription & another box caused same withdrawal symptoms, till I went back to patch from box that was effective. Please is anyone else having these issues. I don't know what to do.